STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5NUD7_SHEEPC-type lectin domain-containing protein. (375 aa)    
Predicted Functional Partners:
SFTPA1
Pulmonary surfactant-associated protein A; In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air- liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Enhances the expression of MYO18A/SP-R210 on alveolar macrophages.
  
0.554
DCN
Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
   
 0.507
SFTPC
Pulmonary surfactant-associated protein C.
   
 
 0.506
CFI
Uncharacterized protein; Belongs to the peptidase S1 family.
   
 0.488
BGN
Biglycan; May be involved in collagen fiber assembly.
    
 0.469
W5P9E1_SHEEP
Uncharacterized protein.
  
 
  0.447
W5PJR0_SHEEP
Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex.
   
  
 0.440
LOC105601867
Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex.
   
  
 0.425
LOC101121216
Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex.
   
  
 0.425
SFTPB
Surfactant protein B.
   
 
 0.407
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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