Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
W5NUE0_SHEEPUbiquitin carboxyl-terminal hydrolase. (487 aa)    
Predicted Functional Partners:
ASXL2
ASXL transcriptional regulator 2.
   
 0.973
ASXL1
ASXL transcriptional regulator 1.
   
 0.941
OGT
O-linked N-acetylglucosamine (GlcNAc) transferase.
    
 0.890
KDM1B
Lysine demethylase 1B.
   
 0.888
BARD1
BRCA1 associated RING domain 1.
    
 0.888
PSMD8
Proteasome 26S subunit, non-ATPase 8.
   
 0.860
ADRM1
Adhesion regulating molecule 1.
    
 0.847
PSMD13
Proteasome 26S subunit, non-ATPase 13.
   
 0.845
PSMD11
Proteasome 26S subunit, non-ATPase 11.
   
 0.833
MBD5
Methyl-CpG binding domain protein 5.
    
 0.830
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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