STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHA2Pleckstrin homology domain containing A2. (428 aa)    
Predicted Functional Partners:
PTPN13
Protein tyrosine phosphatase non-receptor type 13.
    
 0.923
MYSM1
Myb like, SWIRM and MPN domains 1.
    
 0.847
TUBGCP5
Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family.
      
 0.827
IQCG
IQ motif containing G.
      
 0.799
ADAM32
ADAM metallopeptidase domain 32.
      
 0.786
STXBP4
Syntaxin binding protein 4.
    
 
 0.773
SH3RF1
RING-type domain-containing protein.
    
 
 0.754
W5Q1T1_SHEEP
Uncharacterized protein.
    
 
 0.754
UMPS
Uridine monophosphate synthetase.
      
 0.742
HTRA4
HtrA serine peptidase 4.
      
 0.727
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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