STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CD19CD19 molecule. (565 aa)    
Predicted Functional Partners:
CD81
Tetraspanin.
    
 0.999
VAV1
Vav guanine nucleotide exchange factor 1.
   
 0.997
LYN
Tyrosine-protein kinase.
   
 0.991
CD4
T-cell surface glycoprotein CD4; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.
   
 
 0.985
CXCR5
C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family.
  
  
 0.983
CD79A
CD79a molecule.
   
 0.982
SYK
Tyrosine-protein kinase.
   
 0.972
VAV3
Vav guanine nucleotide exchange factor 3.
   
 0.970
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.963
CD40
CD40 molecule.
   
  
 0.950
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.