| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ASNS | CHAC1 | ENSOARP00000005016 | ENSOARP00000021813 | Asparagine synthetase [glutamine-hydrolyzing]. | Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. | 0.851 |
| ASNS | W5NUF7_SHEEP | ENSOARP00000005016 | ENSOARP00000001801 | Asparagine synthetase [glutamine-hydrolyzing]. | Uncharacterized protein. | 0.519 |
| BAG1 | W5NUF7_SHEEP | ENSOARP00000010216 | ENSOARP00000001801 | BCL2 associated athanogene 1. | Uncharacterized protein. | 0.512 |
| CHAC1 | ASNS | ENSOARP00000021813 | ENSOARP00000005016 | Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. | Asparagine synthetase [glutamine-hydrolyzing]. | 0.851 |
| CHAC1 | W5NUF7_SHEEP | ENSOARP00000021813 | ENSOARP00000001801 | Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. | Uncharacterized protein. | 0.512 |
| DDB2 | W5NUF7_SHEEP | ENSOARP00000005861 | ENSOARP00000001801 | Damage specific DNA binding protein 2. | Uncharacterized protein. | 0.589 |
| FLT3 | SOS1 | ENSOARP00000013266 | ENSOARP00000009040 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | SOS Ras/Rac guanine nucleotide exchange factor 1. | 0.451 |
| FLT3 | W5NUF7_SHEEP | ENSOARP00000013266 | ENSOARP00000001801 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Uncharacterized protein. | 0.405 |
| MET | MST1R | ENSOARP00000000815 | ENSOARP00000012165 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Macrophage stimulating 1 receptor. | 0.653 |
| MET | SOS1 | ENSOARP00000000815 | ENSOARP00000009040 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | SOS Ras/Rac guanine nucleotide exchange factor 1. | 0.594 |
| MET | W5NUF7_SHEEP | ENSOARP00000000815 | ENSOARP00000001801 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Uncharacterized protein. | 0.659 |
| MST1R | MET | ENSOARP00000012165 | ENSOARP00000000815 | Macrophage stimulating 1 receptor. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.653 |
| MST1R | SOS1 | ENSOARP00000012165 | ENSOARP00000009040 | Macrophage stimulating 1 receptor. | SOS Ras/Rac guanine nucleotide exchange factor 1. | 0.513 |
| MST1R | W5NUF7_SHEEP | ENSOARP00000012165 | ENSOARP00000001801 | Macrophage stimulating 1 receptor. | Uncharacterized protein. | 0.659 |
| PDGFRA | SOS1 | ENSOARP00000020481 | ENSOARP00000009040 | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. | SOS Ras/Rac guanine nucleotide exchange factor 1. | 0.942 |
| PDGFRA | W5NUF7_SHEEP | ENSOARP00000020481 | ENSOARP00000001801 | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. | Uncharacterized protein. | 0.405 |
| SOS1 | FLT3 | ENSOARP00000009040 | ENSOARP00000013266 | SOS Ras/Rac guanine nucleotide exchange factor 1. | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.451 |
| SOS1 | MET | ENSOARP00000009040 | ENSOARP00000000815 | SOS Ras/Rac guanine nucleotide exchange factor 1. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.594 |
| SOS1 | MST1R | ENSOARP00000009040 | ENSOARP00000012165 | SOS Ras/Rac guanine nucleotide exchange factor 1. | Macrophage stimulating 1 receptor. | 0.513 |
| SOS1 | PDGFRA | ENSOARP00000009040 | ENSOARP00000020481 | SOS Ras/Rac guanine nucleotide exchange factor 1. | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. | 0.942 |