STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALX4ALX homeobox 4. (304 aa)    
Predicted Functional Partners:
HINT2
Histidine triad nucleotide binding protein 2.
      
 0.643
EXT2
Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family.
      
 0.639
GTF2A1
General transcription factor IIA subunit 1.
      
 0.598
NEURL2
Neuralized E3 ubiquitin protein ligase 2.
      
 0.590
STARD9
Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
 
 0.589
PHIP
Pleckstrin homology domain interacting protein.
    
 
 0.582
IRAK1BP1
Interleukin 1 receptor associated kinase 1 binding protein 1.
      
 0.569
LIN52
Lin-52 DREAM MuvB core complex component.
      
 0.537
PRSS53
Serine protease 53; Belongs to the peptidase S1 family.
    
 
 0.536
PPFIA2
PTPRF interacting protein alpha 2.
      
 0.536
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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