| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADIPOQ | CIDEA | ENSOARP00000022034 | ENSOARP00000001815 | C1q domain-containing protein. | Cell death inducing DFFA like effector a. | 0.689 |
| ADIPOQ | CIDEC | ENSOARP00000022034 | ENSOARP00000006303 | C1q domain-containing protein. | Cell death inducing DFFA like effector c. | 0.643 |
| ADIPOQ | COX7A1 | ENSOARP00000022034 | ENSOARP00000005673 | C1q domain-containing protein. | Cytochrome c oxidase subunit 7A1, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembran [...] | 0.413 |
| ADIPOQ | DIO2 | ENSOARP00000022034 | ENSOARP00000002973 | C1q domain-containing protein. | Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). | 0.531 |
| ADIPOQ | ELOVL3 | ENSOARP00000022034 | ENSOARP00000018890 | C1q domain-containing protein. | Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] | 0.476 |
| ADIPOQ | PPARGC1A | ENSOARP00000022034 | ENSOARP00000005990 | C1q domain-containing protein. | PPARG coactivator 1 alpha. | 0.680 |
| ADIPOQ | PRDM16 | ENSOARP00000022034 | ENSOARP00000018502 | C1q domain-containing protein. | PR/SET domain 16. | 0.647 |
| ADIPOQ | TMEM26 | ENSOARP00000022034 | ENSOARP00000004691 | C1q domain-containing protein. | Transmembrane protein 26. | 0.450 |
| ADIPOQ | UCP1 | ENSOARP00000022034 | ENSOARP00000013406 | C1q domain-containing protein. | Mitochondrial brown fat uncoupling protein 1; Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates to non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance (By similarity). Functions as a long-chain fatty acid/LCFA and proton symporter, simultaneously transporting one LCFA and one proton through the inner mitochondrial membrane. However, LCFAs remaining associated with the transporter via their hydrophobic tails, it results in [...] | 0.811 |
| ADIPOQ | W5PFK9_SHEEP | ENSOARP00000022034 | ENSOARP00000009224 | C1q domain-containing protein. | Uncharacterized protein. | 0.528 |
| CIDEA | ADIPOQ | ENSOARP00000001815 | ENSOARP00000022034 | Cell death inducing DFFA like effector a. | C1q domain-containing protein. | 0.689 |
| CIDEA | CIDEC | ENSOARP00000001815 | ENSOARP00000006303 | Cell death inducing DFFA like effector a. | Cell death inducing DFFA like effector c. | 0.939 |
| CIDEA | COX7A1 | ENSOARP00000001815 | ENSOARP00000005673 | Cell death inducing DFFA like effector a. | Cytochrome c oxidase subunit 7A1, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembran [...] | 0.741 |
| CIDEA | DIO2 | ENSOARP00000001815 | ENSOARP00000002973 | Cell death inducing DFFA like effector a. | Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). | 0.759 |
| CIDEA | ELOVL3 | ENSOARP00000001815 | ENSOARP00000018890 | Cell death inducing DFFA like effector a. | Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] | 0.754 |
| CIDEA | PPARGC1A | ENSOARP00000001815 | ENSOARP00000005990 | Cell death inducing DFFA like effector a. | PPARG coactivator 1 alpha. | 0.770 |
| CIDEA | PRDM16 | ENSOARP00000001815 | ENSOARP00000018502 | Cell death inducing DFFA like effector a. | PR/SET domain 16. | 0.864 |
| CIDEA | TMEM26 | ENSOARP00000001815 | ENSOARP00000004691 | Cell death inducing DFFA like effector a. | Transmembrane protein 26. | 0.764 |
| CIDEA | UCP1 | ENSOARP00000001815 | ENSOARP00000013406 | Cell death inducing DFFA like effector a. | Mitochondrial brown fat uncoupling protein 1; Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates to non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance (By similarity). Functions as a long-chain fatty acid/LCFA and proton symporter, simultaneously transporting one LCFA and one proton through the inner mitochondrial membrane. However, LCFAs remaining associated with the transporter via their hydrophobic tails, it results in [...] | 0.902 |
| CIDEA | W5PFK9_SHEEP | ENSOARP00000001815 | ENSOARP00000009224 | Cell death inducing DFFA like effector a. | Uncharacterized protein. | 0.685 |