STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC54Coiled-coil domain containing 54. (328 aa)    
Predicted Functional Partners:
DNAJB8
Uncharacterized protein.
   
  
 0.684
SOX30
SRY-box transcription factor 30.
      
 0.593
TMCO2
Transmembrane and coiled-coil domains 2.
   
  
 0.566
TNP1
Spermatid nuclear transition protein 1; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.
   
  
 0.562
CABS1
Calcium binding protein, spermatid associated 1.
   
  
 0.556
ADAM29
ADAM metallopeptidase domain 29.
   
  
 0.545
ADAM2
ADAM metallopeptidase domain 2.
   
  
 0.537
FAM71F1
Family with sequence similarity 71 member F1.
      
 0.536
W5P3A5_SHEEP
Uncharacterized protein.
      
 0.536
FAM81B
Family with sequence similarity 81 member B.
      
 0.535
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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