STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDH8Cadherin 8; Cadherins are calcium-dependent cell adhesion proteins. (799 aa)    
Predicted Functional Partners:
SORCS3
Sortilin related VPS10 domain containing receptor 3.
   
 
 0.779
JUP
Junction plakoglobin.
    
 0.751
CTNNB1
Catenin beta 1.
    
 0.729
KIRREL3
Kirre like nephrin family adhesion molecule 3.
   
 0.682
CTNND1
Catenin delta 1.
   
 0.671
NTNG1
Netrin G1.
    
 
 0.643
CNIH3
Cornichon family AMPA receptor auxiliary protein 3.
      
 0.605
CTNNA2-2
Uncharacterized protein.
    
 0.603
CTNNA2
Catenin alpha 2.
    
 0.603
W5Q9A6_SHEEP
Uncharacterized protein.
   
 0.573
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.