Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RASD1Ras related dexamethasone induced 1. (268 aa)    
Predicted Functional Partners:
NOS1AP
Nitric oxide synthase 1 adaptor protein.
    
 0.961
GNB2
G protein subunit beta 2.
   
 0.939
NOS1
Nitric oxide synthase, brain; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR (By similarity); Belongs to the NOS family.
    
 0.933
GNAI2
Uncharacterized protein.
   
 0.923
GNAI1
G protein subunit alpha i1.
   
 0.923
GNAO1
G protein subunit alpha o1.
   
 0.923
GNB4
G protein subunit beta 4.
   
 0.917
GNB3
G protein subunit beta 3.
   
 0.915
GNB5
G protein subunit beta 5.
   
 0.915
GNG13
G protein subunit gamma 13.
     
 0.913
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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