STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HTRA4HtrA serine peptidase 4. (476 aa)    
Predicted Functional Partners:
KLHL21
Kelch like family member 21.
     
 0.847
DNAJC11
DnaJ heat shock protein family (Hsp40) member C11.
  
  
 0.756
SCP2
Sterol carrier protein 2.
    
 0.734
TMEM53
Transmembrane protein 53.
      
 0.729
PLEKHA2
Pleckstrin homology domain containing A2.
      
 0.727
HOOK1
Hook microtubule tethering protein 1.
      
 0.716
TNFRSF25
TNF receptor superfamily member 25.
    
 
 0.694
ADAM32
ADAM metallopeptidase domain 32.
      
 0.690
BIRC6
Baculoviral IAP repeat containing 6.
    
 0.677
KATNAL2
Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
   
 0.673
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.