STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NDFIP1Nedd4 family interacting protein 1. (222 aa)    
Predicted Functional Partners:
NEDD4
E3 ubiquitin-protein ligase.
    
 
 0.958
WWP2
E3 ubiquitin-protein ligase.
    
 
 0.777
W5PSS2_SHEEP
E3 ubiquitin-protein ligase.
    
 
 0.676
W5PZ83_SHEEP
E3 ubiquitin-protein ligase.
    
 
 0.676
SMURF2
E3 ubiquitin-protein ligase.
    
 
 0.652
SMURF1
E3 ubiquitin-protein ligase.
    
 
 0.644
PRRG4
Proline rich and Gla domain 4.
      
 0.618
RC3H1
Ring finger and CCCH-type domains 1.
      
 0.609
FAM189B
Family with sequence similarity 189 member B.
   
  
 0.572
NEDD4L
NEDD4 like E3 ubiquitin protein ligase.
    
 
 0.545
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.