STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AOC1Amine oxidase. (332 aa)    
Predicted Functional Partners:
HNMT
Histamine N-methyltransferase.
     
 0.966
MAOB
Amine oxidase.
   
 
 0.963
MAOA
Amine oxidase [flavin-containing] A; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine (By similarity).
   
 
 0.960
HDC
Histidine decarboxylase.
     
 0.952
ODC1
Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
   
 
 0.946
SRM
Spermidine synthase; Belongs to the spermidine/spermine synthase family.
     
 0.935
AGMAT
Agmatinase; Belongs to the arginase family.
     
 0.927
ALDH3A2
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 0.926
ALDH2
Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.
   
 0.925
ALDH9A1
Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.
   
 0.924
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.