CATHL3 protein (Ovis aries) - STRING interaction network

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CATHL3

Cathelicidin-3; Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms (By similarity); Belongs to the cathelicidin family. (190 aa)

Predicted Functional Partners:

NFKB1

0.909

RELA

0.905

NAPB

0.814

W5P1Y8_SHEEP

0.809

SC52_SHEEP

0.731

PGLYRP1

0.649

LTF

0.598

CATHL2

0.581

W5NUU0_SHEEP

0.532

SBD2

0.510

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CATHL2	CATHL3	ENSOARP00000002071	ENSOARP00000001893	Cathelicidin-2; Binds to the lipid A moiety of bacterial lipipolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Potent antimicrobial activity (By similarity); Belongs to the cathelicidin family.	Cathelicidin-3; Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms (By similarity); Belongs to the cathelicidin family.	0.581
CATHL2	LTF	ENSOARP00000002071	ENSOARP00000009256	Cathelicidin-2; Binds to the lipid A moiety of bacterial lipipolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Potent antimicrobial activity (By similarity); Belongs to the cathelicidin family.	Uncharacterized protein; Belongs to the transferrin family.	0.552
CATHL2	NFKB1	ENSOARP00000002071	ENSOARP00000013630	Cathelicidin-2; Binds to the lipid A moiety of bacterial lipipolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Potent antimicrobial activity (By similarity); Belongs to the cathelicidin family.	Nuclear factor kappa B subunit 1.	0.909
CATHL2	PGLYRP1	ENSOARP00000002071	ENSOARP00000011240	Cathelicidin-2; Binds to the lipid A moiety of bacterial lipipolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Potent antimicrobial activity (By similarity); Belongs to the cathelicidin family.	Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity.	0.548
CATHL2	RELA	ENSOARP00000002071	ENSOARP00000018707	Cathelicidin-2; Binds to the lipid A moiety of bacterial lipipolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Potent antimicrobial activity (By similarity); Belongs to the cathelicidin family.	RELA proto-oncogene, NF-kB subunit.	0.905
CATHL2	SBD2	ENSOARP00000002071	ENSOARP00000006894	Cathelicidin-2; Binds to the lipid A moiety of bacterial lipipolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Potent antimicrobial activity (By similarity); Belongs to the cathelicidin family.	Beta-defensin 2; Has bactericidal activity; Belongs to the beta-defensin family.	0.571
CATHL2	SC52_SHEEP	ENSOARP00000002071	ENSOARP00000002274	Cathelicidin-2; Binds to the lipid A moiety of bacterial lipipolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Potent antimicrobial activity (By similarity); Belongs to the cathelicidin family.	Cathelin-related peptide SC5; Broad spectrum bactericidal agent.	0.748
CATHL2	W5NUU0_SHEEP	ENSOARP00000002071	ENSOARP00000001934	Cathelicidin-2; Binds to the lipid A moiety of bacterial lipipolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Potent antimicrobial activity (By similarity); Belongs to the cathelicidin family.	Uncharacterized protein.	0.532
CATHL2	W5P1Y8_SHEEP	ENSOARP00000002071	ENSOARP00000004437	Cathelicidin-2; Binds to the lipid A moiety of bacterial lipipolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Potent antimicrobial activity (By similarity); Belongs to the cathelicidin family.	Uncharacterized protein.	0.809
CATHL3	CATHL2	ENSOARP00000001893	ENSOARP00000002071	Cathelicidin-3; Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms (By similarity); Belongs to the cathelicidin family.	Cathelicidin-2; Binds to the lipid A moiety of bacterial lipipolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Potent antimicrobial activity (By similarity); Belongs to the cathelicidin family.	0.581
CATHL3	LTF	ENSOARP00000001893	ENSOARP00000009256	Cathelicidin-3; Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms (By similarity); Belongs to the cathelicidin family.	Uncharacterized protein; Belongs to the transferrin family.	0.598
CATHL3	NAPB	ENSOARP00000001893	ENSOARP00000005879	Cathelicidin-3; Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms (By similarity); Belongs to the cathelicidin family.	NSF attachment protein beta.	0.814
CATHL3	NFKB1	ENSOARP00000001893	ENSOARP00000013630	Cathelicidin-3; Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms (By similarity); Belongs to the cathelicidin family.	Nuclear factor kappa B subunit 1.	0.909
CATHL3	PGLYRP1	ENSOARP00000001893	ENSOARP00000011240	Cathelicidin-3; Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms (By similarity); Belongs to the cathelicidin family.	Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity.	0.649
CATHL3	RELA	ENSOARP00000001893	ENSOARP00000018707	Cathelicidin-3; Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms (By similarity); Belongs to the cathelicidin family.	RELA proto-oncogene, NF-kB subunit.	0.905
CATHL3	SBD2	ENSOARP00000001893	ENSOARP00000006894	Cathelicidin-3; Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms (By similarity); Belongs to the cathelicidin family.	Beta-defensin 2; Has bactericidal activity; Belongs to the beta-defensin family.	0.510
CATHL3	SC52_SHEEP	ENSOARP00000001893	ENSOARP00000002274	Cathelicidin-3; Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms (By similarity); Belongs to the cathelicidin family.	Cathelin-related peptide SC5; Broad spectrum bactericidal agent.	0.731
CATHL3	W5NUU0_SHEEP	ENSOARP00000001893	ENSOARP00000001934	Cathelicidin-3; Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms (By similarity); Belongs to the cathelicidin family.	Uncharacterized protein.	0.532
CATHL3	W5P1Y8_SHEEP	ENSOARP00000001893	ENSOARP00000004437	Cathelicidin-3; Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms (By similarity); Belongs to the cathelicidin family.	Uncharacterized protein.	0.809
LTF	CATHL2	ENSOARP00000009256	ENSOARP00000002071	Uncharacterized protein; Belongs to the transferrin family.	Cathelicidin-2; Binds to the lipid A moiety of bacterial lipipolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Potent antimicrobial activity (By similarity); Belongs to the cathelicidin family.	0.552

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