TNNI3 protein (Ovis aries) - STRING interaction network

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Predicted Interactions

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Score

TNNI3

Troponin I3, cardiac type. (212 aa)

Predicted Functional Partners:

TNNC1

0.998

TPM1

0.977

TPM4

0.966

TPM3

0.966

TPM2

0.966

PRKACA

0.954

PRKACB

0.954

TNNT1

0.949

W5QBX2_SHEEP

0.947

TNNT3

0.926

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PRKACA	PRKACB	ENSOARP00000006933	ENSOARP00000014812	cAMP-dependent protein kinase catalytic subunit alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose- mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in the [...]	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.900
PRKACA	TNNI3	ENSOARP00000006933	ENSOARP00000001898	cAMP-dependent protein kinase catalytic subunit alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose- mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in the [...]	Troponin I3, cardiac type.	0.954
PRKACB	PRKACA	ENSOARP00000014812	ENSOARP00000006933	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	cAMP-dependent protein kinase catalytic subunit alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose- mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in the [...]	0.900
PRKACB	TNNI3	ENSOARP00000014812	ENSOARP00000001898	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	Troponin I3, cardiac type.	0.954
TNNC1	TNNI3	ENSOARP00000004614	ENSOARP00000001898	Troponin C1, slow skeletal and cardiac type.	Troponin I3, cardiac type.	0.998
TNNC1	TNNT1	ENSOARP00000004614	ENSOARP00000001911	Troponin C1, slow skeletal and cardiac type.	Troponin T1, slow skeletal type.	0.888
TNNC1	TNNT3	ENSOARP00000004614	ENSOARP00000000717	Troponin C1, slow skeletal and cardiac type.	Troponin T3, fast skeletal type.	0.894
TNNC1	TPM1	ENSOARP00000004614	ENSOARP00000022353	Troponin C1, slow skeletal and cardiac type.	Uncharacterized protein; Belongs to the tropomyosin family.	0.605
TNNC1	TPM2	ENSOARP00000004614	ENSOARP00000012741	Troponin C1, slow skeletal and cardiac type.	Uncharacterized protein; Belongs to the tropomyosin family.	0.651
TNNC1	TPM3	ENSOARP00000004614	ENSOARP00000001937	Troponin C1, slow skeletal and cardiac type.	Tropomyosin 3; Belongs to the tropomyosin family.	0.801
TNNC1	TPM4	ENSOARP00000004614	ENSOARP00000000904	Troponin C1, slow skeletal and cardiac type.	Tropomyosin 4; Belongs to the tropomyosin family.	0.605
TNNC1	W5QBX2_SHEEP	ENSOARP00000004614	ENSOARP00000020219	Troponin C1, slow skeletal and cardiac type.	Uncharacterized protein.	0.913
TNNI3	PRKACA	ENSOARP00000001898	ENSOARP00000006933	Troponin I3, cardiac type.	cAMP-dependent protein kinase catalytic subunit alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose- mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in the [...]	0.954
TNNI3	PRKACB	ENSOARP00000001898	ENSOARP00000014812	Troponin I3, cardiac type.	Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.	0.954
TNNI3	TNNC1	ENSOARP00000001898	ENSOARP00000004614	Troponin I3, cardiac type.	Troponin C1, slow skeletal and cardiac type.	0.998
TNNI3	TNNT1	ENSOARP00000001898	ENSOARP00000001911	Troponin I3, cardiac type.	Troponin T1, slow skeletal type.	0.949
TNNI3	TNNT3	ENSOARP00000001898	ENSOARP00000000717	Troponin I3, cardiac type.	Troponin T3, fast skeletal type.	0.926
TNNI3	TPM1	ENSOARP00000001898	ENSOARP00000022353	Troponin I3, cardiac type.	Uncharacterized protein; Belongs to the tropomyosin family.	0.977
TNNI3	TPM2	ENSOARP00000001898	ENSOARP00000012741	Troponin I3, cardiac type.	Uncharacterized protein; Belongs to the tropomyosin family.	0.966
TNNI3	TPM3	ENSOARP00000001898	ENSOARP00000001937	Troponin I3, cardiac type.	Tropomyosin 3; Belongs to the tropomyosin family.	0.966