W5NUR1_SHEEP protein (Ovis aries) - STRING interaction network

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Score

W5NUR1_SHEEP

IRF tryptophan pentad repeat domain-containing protein. (405 aa)

Predicted Functional Partners:

SNED1

0.515

IRF1

0.513

LMCD1

0.482

MYD88

0.422

SPI1

0.407

W5PW48_SHEEP

0.407

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IRF1	MYD88	ENSOARP00000016180	ENSOARP00000001070	Interferon regulatory factor.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...]	0.798
IRF1	SPI1	ENSOARP00000016180	ENSOARP00000007015	Interferon regulatory factor.	Spi-1 proto-oncogene.	0.550
IRF1	W5NUR1_SHEEP	ENSOARP00000016180	ENSOARP00000001905	Interferon regulatory factor.	IRF tryptophan pentad repeat domain-containing protein.	0.513
IRF1	W5PW48_SHEEP	ENSOARP00000016180	ENSOARP00000014681	Interferon regulatory factor.	ETS domain-containing protein.	0.456
LMCD1	W5NUR1_SHEEP	ENSOARP00000008193	ENSOARP00000001905	LIM and cysteine rich domains 1.	IRF tryptophan pentad repeat domain-containing protein.	0.482
MYD88	IRF1	ENSOARP00000001070	ENSOARP00000016180	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...]	Interferon regulatory factor.	0.798
MYD88	W5NUR1_SHEEP	ENSOARP00000001070	ENSOARP00000001905	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...]	IRF tryptophan pentad repeat domain-containing protein.	0.422
SNED1	W5NUR1_SHEEP	ENSOARP00000019478	ENSOARP00000001905	Sushi, nidogen and EGF like domains 1.	IRF tryptophan pentad repeat domain-containing protein.	0.515
SPI1	IRF1	ENSOARP00000007015	ENSOARP00000016180	Spi-1 proto-oncogene.	Interferon regulatory factor.	0.550
SPI1	W5NUR1_SHEEP	ENSOARP00000007015	ENSOARP00000001905	Spi-1 proto-oncogene.	IRF tryptophan pentad repeat domain-containing protein.	0.407
W5NUR1_SHEEP	IRF1	ENSOARP00000001905	ENSOARP00000016180	IRF tryptophan pentad repeat domain-containing protein.	Interferon regulatory factor.	0.513
W5NUR1_SHEEP	LMCD1	ENSOARP00000001905	ENSOARP00000008193	IRF tryptophan pentad repeat domain-containing protein.	LIM and cysteine rich domains 1.	0.482
W5NUR1_SHEEP	MYD88	ENSOARP00000001905	ENSOARP00000001070	IRF tryptophan pentad repeat domain-containing protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...]	0.422
W5NUR1_SHEEP	SNED1	ENSOARP00000001905	ENSOARP00000019478	IRF tryptophan pentad repeat domain-containing protein.	Sushi, nidogen and EGF like domains 1.	0.515
W5NUR1_SHEEP	SPI1	ENSOARP00000001905	ENSOARP00000007015	IRF tryptophan pentad repeat domain-containing protein.	Spi-1 proto-oncogene.	0.407
W5NUR1_SHEEP	W5PW48_SHEEP	ENSOARP00000001905	ENSOARP00000014681	IRF tryptophan pentad repeat domain-containing protein.	ETS domain-containing protein.	0.407
W5PW48_SHEEP	IRF1	ENSOARP00000014681	ENSOARP00000016180	ETS domain-containing protein.	Interferon regulatory factor.	0.456
W5PW48_SHEEP	W5NUR1_SHEEP	ENSOARP00000014681	ENSOARP00000001905	ETS domain-containing protein.	IRF tryptophan pentad repeat domain-containing protein.	0.407