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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFXN2Sidoreflexin. (325 aa)    
Predicted Functional Partners:
C12orf73
Chromosome 12 open reading frame 73.
   
 
 0.579
SFXN4
Sideroflexin 4.
  
 
 
0.575
RALGPS1
Ral GEF with PH domain and SH3 binding motif 1.
      
 0.567
PRRC2A
Proline rich coiled-coil 2A.
      
 0.535
PRKAG1
Protein kinase AMP-activated non-catalytic subunit gamma 1.
      
 0.535
WBP1L
WW domain binding protein 1 like.
      
 0.534
MTBP
MDM2 binding protein.
      
 0.533
EIF6
Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...]
   
  
 0.524
W5P489_SHEEP
Uncharacterized protein.
      
 0.520
TIMM22
Translocase of inner mitochondrial membrane 22.
   
  
 0.520
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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