STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RASGEF1CRasGEF domain family member 1C. (381 aa)    
Predicted Functional Partners:
ISOC1
Isochorismatase domain containing 1.
      
 0.835
LIX1
Limb and CNS expressed 1.
      
 0.823
PLCH1
Phosphoinositide phospholipase C.
      
 0.747
CASZ1
Castor zinc finger 1.
      
 0.664
FAM13B
Family with sequence similarity 13 member B.
      
 0.628
RUFY1
Uncharacterized protein.
      
 0.587
MECOM
MDS1 and EVI1 complex locus.
      
 0.581
LHX4
LIM homeobox 4.
      
 0.571
RXRG
Retinoid X receptor gamma.
   
 
 0.567
KCNS2
Potassium voltage-gated channel modifier subfamily S member 2; Belongs to the potassium channel family.
      
 0.567
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.