STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GAP43Growth associated protein 43. (192 aa)    
Predicted Functional Partners:
LYPLA2
Lysophospholipase 2.
     
 0.851
NGF
Nerve growth factor; Belongs to the NGF-beta family.
      
 0.789
TH
Tyrosine hydroxylase.
      
 0.778
SYP
Synaptophysin.
   
  
 0.749
STMN2
Stathmin; Belongs to the stathmin family.
   
  
 0.742
MAP2
Microtubule-associated protein.
   
 
 0.727
BDNF
Brain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.
      
 0.724
GFAP
Glial fibrillary acidic protein; Belongs to the intermediate filament family.
   
  
 0.720
ATF3
Activating transcription factor 3.
   
  
 0.713
SNAP25
Synaptosomal-associated protein; Belongs to the SNAP-25 family.
   
  
 0.670
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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