Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (404 aa)    
Predicted Functional Partners:
PIP4K2C
Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma.
  
 
0.999
PIP4K2B
Phosphatidylinositol-5-phosphate 4-kinase type 2 beta.
  
0.999
SYNJ1
Synaptojanin 1.
    
 0.955
PIP5K1B
Phosphatidylinositol-4-phosphate 5-kinase type 1 beta.
    
0.942
PIP5K1C
Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma.
    
0.941
PIK3CG
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.
     
 0.940
PIP5K1A
Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha.
    
0.940
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
     
 0.935
PIP4P2
Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
     
 0.932
PIP4P1
Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
     
 0.932
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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