STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRRC18Leucine rich repeat containing 18. (263 aa)    
Predicted Functional Partners:
DRG2
Developmentally regulated GTP binding protein 2.
      
 0.918
POLR2E
RNA polymerase II subunit E.
    
 
 0.903
MAP7
Microtubule associated protein 7.
    
 0.831
LRGUK
Leucine rich repeats and guanylate kinase domain containing.
   
 0.804
NEK5
NIMA related kinase 5.
   
  0.780
TRIM32
Tripartite motif containing 32.
    
 
 0.775
RNF141
Ring finger protein 141.
      
 0.711
WDFY4
WDFY family member 4.
    
 
 0.691
ADGRL1
Olfactomedin-like domain-containing protein.
    
   0.674
ADGRL3
Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.
    
   0.674
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.