W5NUW5_SHEEP protein (Ovis aries) - STRING interaction network

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

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Score

W5NUW5_SHEEP

Uncharacterized protein. (144 aa)

Predicted Functional Partners:

MPRIP

0.887

TCAP

0.692

MED9

0.655

W5Q5E0_SHEEP

0.632

W5NRS0_SHEEP

0.628

NME6

0.613

MTAP

0.608

TWISTNB

0.535

POLR1A

0.535

DHODH

0.532

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DHODH	MTAP	ENSOARP00000004015	ENSOARP00000015465	Dihydroorotate dehydrogenase (quinone).	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	0.405
DHODH	NME6	ENSOARP00000004015	ENSOARP00000001136	Dihydroorotate dehydrogenase (quinone).	Nucleoside diphosphate kinase.	0.534
DHODH	POLR1A	ENSOARP00000004015	ENSOARP00000022139	Dihydroorotate dehydrogenase (quinone).	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.443
DHODH	W5NRS0_SHEEP	ENSOARP00000004015	ENSOARP00000000860	Dihydroorotate dehydrogenase (quinone).	PNP_UDP_1 domain-containing protein.	0.415
DHODH	W5NUW5_SHEEP	ENSOARP00000004015	ENSOARP00000001960	Dihydroorotate dehydrogenase (quinone).	Uncharacterized protein.	0.532
MED9	W5NUW5_SHEEP	ENSOARP00000001916	ENSOARP00000001960	Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Uncharacterized protein.	0.655
MPRIP	TCAP	ENSOARP00000002337	ENSOARP00000012406	Myosin phosphatase Rho interacting protein.	Titin-cap.	0.455
MPRIP	W5NUW5_SHEEP	ENSOARP00000002337	ENSOARP00000001960	Myosin phosphatase Rho interacting protein.	Uncharacterized protein.	0.887
MPRIP	W5Q5E0_SHEEP	ENSOARP00000002337	ENSOARP00000017930	Myosin phosphatase Rho interacting protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.807
MTAP	DHODH	ENSOARP00000015465	ENSOARP00000004015	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	Dihydroorotate dehydrogenase (quinone).	0.405
MTAP	W5NRS0_SHEEP	ENSOARP00000015465	ENSOARP00000000860	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	PNP_UDP_1 domain-containing protein.	0.442
MTAP	W5NUW5_SHEEP	ENSOARP00000015465	ENSOARP00000001960	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.	Uncharacterized protein.	0.608
NME6	DHODH	ENSOARP00000001136	ENSOARP00000004015	Nucleoside diphosphate kinase.	Dihydroorotate dehydrogenase (quinone).	0.534
NME6	W5NUW5_SHEEP	ENSOARP00000001136	ENSOARP00000001960	Nucleoside diphosphate kinase.	Uncharacterized protein.	0.613
POLR1A	DHODH	ENSOARP00000022139	ENSOARP00000004015	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Dihydroorotate dehydrogenase (quinone).	0.443
POLR1A	TWISTNB	ENSOARP00000022139	ENSOARP00000010509	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	TWIST neighbor.	0.998
POLR1A	W5NUW5_SHEEP	ENSOARP00000022139	ENSOARP00000001960	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	Uncharacterized protein.	0.535
TCAP	MPRIP	ENSOARP00000012406	ENSOARP00000002337	Titin-cap.	Myosin phosphatase Rho interacting protein.	0.455
TCAP	W5NUW5_SHEEP	ENSOARP00000012406	ENSOARP00000001960	Titin-cap.	Uncharacterized protein.	0.692
TCAP	W5Q5E0_SHEEP	ENSOARP00000012406	ENSOARP00000017930	Titin-cap.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.545