Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
W5NUX1_SHEEPCullin_Nedd8 domain-containing protein. (206 aa)    
Predicted Functional Partners:
FBXW8
F-box and WD repeat domain containing 8.
   
 0.963
RBX1
Ring-box 1.
   
 0.946
CUL9
Cullin 9; Belongs to the cullin family.
   
  0.906
MRPL20
Mitochondrial ribosomal protein L20; Belongs to the bacterial ribosomal protein bL20 family.
   
 0.888
MRPL17
Mitochondrial ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family.
  
 0.882
MRPL16
Mitochondrial ribosomal protein L16; Belongs to the universal ribosomal protein uL16 family.
  
 0.877
MRPL21
Mitochondrial ribosomal protein L21.
   
 0.869
MRPL9
Mitochondrial ribosomal protein L9.
  
 0.869
MRPL19
Mitochondrial ribosomal protein L19.
   
 0.866
MRPL12
Mitochondrial ribosomal protein L12.
  
 0.856
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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