Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
W5NUX6_SHEEPUncharacterized protein. (158 aa)    
Predicted Functional Partners:
CYP51A1
Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family.
   
 
 0.825
HSD17B7
Hydroxysteroid 17-beta dehydrogenase 7.
   
 
 0.728
SIGMAR1
Sigma non-opioid intracellular receptor 1.
   
 
 0.720
LSS
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
    
 
 0.706
W5PA17_SHEEP
Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.
   
 
 0.609
W5QA41_SHEEP
Uncharacterized protein.
   
 
 0.609
NSDHL
NAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family.
   
 
 0.600
W5NVX2_SHEEP
Uncharacterized protein.
   
 
 0.599
FDFT1
Uncharacterized protein.
   
 
 0.599
FAXDC2
Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family.
   
 
 0.552
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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