IZUMO1R protein (Ovis aries) - STRING interaction network

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Score

IZUMO1R

IZUMO1 receptor, JUNO. (237 aa)

Predicted Functional Partners:

IZUMO1

0.885

MASP2

0.622

IKZF2

0.538

PRNP

0.483

ALB

0.477

TFRC

0.472

CTLA4

0.459

ICOS

0.457

CCR9

0.451

SLC46A1

0.444

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALB	CTLA4	ENSOARP00000014782	ENSOARP00000019665	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Cytotoxic T-lymphocyte-associated protein 4.	0.631
ALB	ICOS	ENSOARP00000014782	ENSOARP00000019671	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Inducible T cell costimulator.	0.420
ALB	IZUMO1R	ENSOARP00000014782	ENSOARP00000001993	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	IZUMO1 receptor, JUNO.	0.477
ALB	PRNP	ENSOARP00000014782	ENSOARP00000004991	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Major prion protein; Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan s [...]	0.524
ALB	TFRC	ENSOARP00000014782	ENSOARP00000021809	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Transferrin receptor.	0.714
CCR9	CTLA4	ENSOARP00000010208	ENSOARP00000019665	C-C chemokine receptor type 9; Receptor for chemokine SCYA25/TECK. Subsequently transduces a signal by increasing the intracellular calcium ions level (By similarity); Belongs to the G-protein coupled receptor 1 family.	Cytotoxic T-lymphocyte-associated protein 4.	0.425
CCR9	IZUMO1R	ENSOARP00000010208	ENSOARP00000001993	C-C chemokine receptor type 9; Receptor for chemokine SCYA25/TECK. Subsequently transduces a signal by increasing the intracellular calcium ions level (By similarity); Belongs to the G-protein coupled receptor 1 family.	IZUMO1 receptor, JUNO.	0.451
CTLA4	ALB	ENSOARP00000019665	ENSOARP00000014782	Cytotoxic T-lymphocyte-associated protein 4.	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	0.631
CTLA4	CCR9	ENSOARP00000019665	ENSOARP00000010208	Cytotoxic T-lymphocyte-associated protein 4.	C-C chemokine receptor type 9; Receptor for chemokine SCYA25/TECK. Subsequently transduces a signal by increasing the intracellular calcium ions level (By similarity); Belongs to the G-protein coupled receptor 1 family.	0.425
CTLA4	ICOS	ENSOARP00000019665	ENSOARP00000019671	Cytotoxic T-lymphocyte-associated protein 4.	Inducible T cell costimulator.	0.954
CTLA4	IKZF2	ENSOARP00000019665	ENSOARP00000020681	Cytotoxic T-lymphocyte-associated protein 4.	IKAROS family zinc finger 2.	0.504
CTLA4	IZUMO1R	ENSOARP00000019665	ENSOARP00000001993	Cytotoxic T-lymphocyte-associated protein 4.	IZUMO1 receptor, JUNO.	0.459
ICOS	ALB	ENSOARP00000019671	ENSOARP00000014782	Inducible T cell costimulator.	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	0.420
ICOS	CTLA4	ENSOARP00000019671	ENSOARP00000019665	Inducible T cell costimulator.	Cytotoxic T-lymphocyte-associated protein 4.	0.954
ICOS	IKZF2	ENSOARP00000019671	ENSOARP00000020681	Inducible T cell costimulator.	IKAROS family zinc finger 2.	0.444
ICOS	IZUMO1R	ENSOARP00000019671	ENSOARP00000001993	Inducible T cell costimulator.	IZUMO1 receptor, JUNO.	0.457
IKZF2	CTLA4	ENSOARP00000020681	ENSOARP00000019665	IKAROS family zinc finger 2.	Cytotoxic T-lymphocyte-associated protein 4.	0.504
IKZF2	ICOS	ENSOARP00000020681	ENSOARP00000019671	IKAROS family zinc finger 2.	Inducible T cell costimulator.	0.444
IKZF2	IZUMO1R	ENSOARP00000020681	ENSOARP00000001993	IKAROS family zinc finger 2.	IZUMO1 receptor, JUNO.	0.538
IZUMO1	IZUMO1R	ENSOARP00000013009	ENSOARP00000001993	Izumo-Ig domain-containing protein.	IZUMO1 receptor, JUNO.	0.885