STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FSCN3Fascin. (498 aa)    
Predicted Functional Partners:
IQCF1
IQ motif containing F1.
      
 0.774
KLHL10
Kelch like family member 10.
   
  
 0.701
CCDC83
Coiled-coil domain containing 83.
      
 0.659
CCDC155
Coiled-coil domain containing 155.
      
 0.656
CCDC182
Coiled-coil domain containing 182.
      
 0.654
TNP2
Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.
      
 0.586
NDRG1
N-myc downstream regulated 1.
   
  
 0.543
IQCG
IQ motif containing G.
      
 0.543
ACTRT2
Actin related protein T2; Belongs to the actin family.
      
 0.538
DMRTC2
DMRT like family C2.
      
 0.528
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.