Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABCG2ABC transporter domain-containing protein. (685 aa)    
Predicted Functional Partners:
ABCC2
ATP binding cassette subfamily C member 2.
   
 0.983
ABCC1
ATP binding cassette subfamily C member 1.
   
 0.953
ABCB1
Uncharacterized protein.
   
 0.851
ABCB1-2
ABC transmembrane type-1 domain-containing protein.
   
 0.848
ABCC6
ATP binding cassette subfamily C member 6.
   
 0.749
W5Q4C8_SHEEP
Uncharacterized protein.
   
 0.746
ABCG5
ATP binding cassette subfamily G member 5.
   
 0.716
LCORL
Ligand dependent nuclear receptor corepressor like.
   
  
 0.700
NCAPG
Non-SMC condensin I complex subunit G.
      
 0.699
BMI1
RING-type domain-containing protein.
    
 
 0.644
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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