STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EPS8L1EPS8 like 1. (727 aa)    
Predicted Functional Partners:
TWF2
Twinfilin actin binding protein 2.
     
 0.764
KPRP
Keratinocyte proline rich protein.
      
 0.763
SIPA1
Signal-induced proliferation-associated 1.
      
 0.722
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
   
 0.673
MYO3A
Myosin IIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.670
W5QC58_SHEEP
ANK_REP_REGION domain-containing protein.
     
 0.627
TWF1
Twinfilin actin binding protein 1.
     
 0.609
PIK3C2B
Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family.
      
 0.595
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
   
 
 0.584
CASP14
Caspase 14; Belongs to the peptidase C14A family.
   
  
 0.561
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.