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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5NV60_SHEEPFA_desaturase domain-containing protein. (169 aa)    
Predicted Functional Partners:
FDX1
Adrenodoxin; Essential for the synthesis of various steroid hormones. Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage. Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons. Belongs to the adrenodoxin/putidaredoxin family.
  
 
 0.554
FDX2
2Fe-2S ferredoxin-type domain-containing protein.
  
 
 0.554
LOC101119959
Uncharacterized protein.
      
 0.553
W5Q1P7_SHEEP
Olfactory receptor.
      
 0.538
EBP
EXPERA domain-containing protein.
   
  
 0.535
EFHC2
EF-hand domain containing 2.
      
 0.513
MARVELD3
MARVEL domain containing 3.
      
 0.512
MAPK1IP1L
Mitogen-activated protein kinase 1 interacting protein 1 like.
     
 0.507
FAM172A
Family with sequence similarity 172 member A.
      
 0.505
W5PA17_SHEEP
Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.
  
 
 0.482
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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