CATHL2 protein (Ovis aries) - STRING interaction network

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CATHL2

Cathelicidin-2; Binds to the lipid A moiety of bacterial lipipolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Potent antimicrobial activity (By similarity); Belongs to the cathelicidin family. (186 aa)

Predicted Functional Partners:

LOC101112427

0.992

CATHL3

0.955

NFKB1

0.911

RELA

0.903

PGBD1

0.750

SC52_SHEEP

0.700

W5P1Y8_SHEEP

0.680

OVCH2

0.628

DEFB125

0.608

W5NR98_SHEEP

0.589

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CATHL2	CATHL3	ENSOARP00000002071	ENSOARP00000001893	Cathelicidin-2; Binds to the lipid A moiety of bacterial lipipolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Potent antimicrobial activity (By similarity); Belongs to the cathelicidin family.	Cathelicidin-3; Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms (By similarity); Belongs to the cathelicidin family.	0.955
CATHL2	DEFB125	ENSOARP00000002071	ENSOARP00000000159	Cathelicidin-2; Binds to the lipid A moiety of bacterial lipipolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Potent antimicrobial activity (By similarity); Belongs to the cathelicidin family.	Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.	0.608
CATHL2	LOC101112427	ENSOARP00000002071	ENSOARP00000001337	Cathelicidin-2; Binds to the lipid A moiety of bacterial lipipolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Potent antimicrobial activity (By similarity); Belongs to the cathelicidin family.	CAP18_C domain-containing protein.	0.992
CATHL2	NFKB1	ENSOARP00000002071	ENSOARP00000013630	Cathelicidin-2; Binds to the lipid A moiety of bacterial lipipolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Potent antimicrobial activity (By similarity); Belongs to the cathelicidin family.	Nuclear factor kappa B subunit 1.	0.911
CATHL2	OVCH2	ENSOARP00000002071	ENSOARP00000016704	Cathelicidin-2; Binds to the lipid A moiety of bacterial lipipolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Potent antimicrobial activity (By similarity); Belongs to the cathelicidin family.	Ovochymase 2 (gene/pseudogene); Belongs to the peptidase S1 family.	0.628
CATHL2	PGBD1	ENSOARP00000002071	ENSOARP00000019200	Cathelicidin-2; Binds to the lipid A moiety of bacterial lipipolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Potent antimicrobial activity (By similarity); Belongs to the cathelicidin family.	PiggyBac transposable element derived 1.	0.750
CATHL2	RELA	ENSOARP00000002071	ENSOARP00000018707	Cathelicidin-2; Binds to the lipid A moiety of bacterial lipipolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Potent antimicrobial activity (By similarity); Belongs to the cathelicidin family.	RELA proto-oncogene, NF-kB subunit.	0.903
CATHL2	SC52_SHEEP	ENSOARP00000002071	ENSOARP00000002274	Cathelicidin-2; Binds to the lipid A moiety of bacterial lipipolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Potent antimicrobial activity (By similarity); Belongs to the cathelicidin family.	Cathelin-related peptide SC5; Broad spectrum bactericidal agent.	0.700
CATHL2	W5NR98_SHEEP	ENSOARP00000002071	ENSOARP00000000688	Cathelicidin-2; Binds to the lipid A moiety of bacterial lipipolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Potent antimicrobial activity (By similarity); Belongs to the cathelicidin family.	Histone H2B; Belongs to the histone H2B family.	0.589
CATHL2	W5P1Y8_SHEEP	ENSOARP00000002071	ENSOARP00000004437	Cathelicidin-2; Binds to the lipid A moiety of bacterial lipipolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Potent antimicrobial activity (By similarity); Belongs to the cathelicidin family.	Uncharacterized protein.	0.680
CATHL3	CATHL2	ENSOARP00000001893	ENSOARP00000002071	Cathelicidin-3; Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms (By similarity); Belongs to the cathelicidin family.	Cathelicidin-2; Binds to the lipid A moiety of bacterial lipipolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Potent antimicrobial activity (By similarity); Belongs to the cathelicidin family.	0.955
CATHL3	LOC101112427	ENSOARP00000001893	ENSOARP00000001337	Cathelicidin-3; Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms (By similarity); Belongs to the cathelicidin family.	CAP18_C domain-containing protein.	0.940
CATHL3	NFKB1	ENSOARP00000001893	ENSOARP00000013630	Cathelicidin-3; Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms (By similarity); Belongs to the cathelicidin family.	Nuclear factor kappa B subunit 1.	0.912
CATHL3	RELA	ENSOARP00000001893	ENSOARP00000018707	Cathelicidin-3; Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms (By similarity); Belongs to the cathelicidin family.	RELA proto-oncogene, NF-kB subunit.	0.903
CATHL3	SC52_SHEEP	ENSOARP00000001893	ENSOARP00000002274	Cathelicidin-3; Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms (By similarity); Belongs to the cathelicidin family.	Cathelin-related peptide SC5; Broad spectrum bactericidal agent.	0.688
CATHL3	W5P1Y8_SHEEP	ENSOARP00000001893	ENSOARP00000004437	Cathelicidin-3; Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms (By similarity); Belongs to the cathelicidin family.	Uncharacterized protein.	0.698
DEFB125	CATHL2	ENSOARP00000000159	ENSOARP00000002071	Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.	Cathelicidin-2; Binds to the lipid A moiety of bacterial lipipolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Potent antimicrobial activity (By similarity); Belongs to the cathelicidin family.	0.608
LOC101112427	CATHL2	ENSOARP00000001337	ENSOARP00000002071	CAP18_C domain-containing protein.	Cathelicidin-2; Binds to the lipid A moiety of bacterial lipipolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Potent antimicrobial activity (By similarity); Belongs to the cathelicidin family.	0.992
LOC101112427	CATHL3	ENSOARP00000001337	ENSOARP00000001893	CAP18_C domain-containing protein.	Cathelicidin-3; Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms (By similarity); Belongs to the cathelicidin family.	0.940
LOC101112427	NFKB1	ENSOARP00000001337	ENSOARP00000013630	CAP18_C domain-containing protein.	Nuclear factor kappa B subunit 1.	0.912

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