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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF130Ring finger protein 130. (396 aa)    
Predicted Functional Partners:
PTPN2
Tyrosine-protein phosphatase non-receptor type.
    
 
 0.597
W5NUX5_SHEEP
TPR_REGION domain-containing protein.
      
 0.538
W5P7L9_SHEEP
Uncharacterized protein.
      
 0.538
CPEB3
Cytoplasmic polyadenylation element binding protein 3.
      
 0.538
ATP2A2
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
    
 
 0.537
GRAMD4
GRAM domain containing 4.
   
  
 0.536
GTF2H5
General transcription factor IIH subunit 5.
     
 0.535
ITSN1
Intersectin 1.
      
 0.535
FAM131B
Family with sequence similarity 131 member B.
      
 0.527
UBXN4
UBX domain protein 4.
      
 0.478
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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