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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5NVA7_SHEEPNeur_chan_memb domain-containing protein. (102 aa)    
Predicted Functional Partners:
SLURP1
UPAR/Ly6 domain-containing protein.
     
 0.901
CHRNA1
Cholinergic receptor nicotinic alpha 1 subunit.
   
 0.616
CAB39L
Calcium binding protein 39 like.
      
 0.568
W5NPM0_SHEEP
Uncharacterized protein.
   
0.559
GJB2
Gap junction beta-2 protein; Structural component of gap junctions (By similarity). Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane (By similarity). Small molecules and ions diffuse from one cell to a neighboring cell via the central pore (By similarity).
      
 0.509
CHRNA9
Cholinergic receptor nicotinic alpha 9 subunit.
     
0.500
W5P0A2_SHEEP
c-SKI_SMAD_bind domain-containing protein.
      
 0.485
POU3F4
POU domain protein.
      
 0.482
SLC26A5
Prestin; Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
      
 0.482
TMC2
Transmembrane channel-like protein.
    
 
 0.481
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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