STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIGLEC1Sialic acid binding Ig like lectin 1. (1701 aa)    
Predicted Functional Partners:
SIGLEC15
Sialic acid binding Ig like lectin 15.
    
 0.859
CD163
CD163 molecule.
   
 0.855
GP5
Glycoprotein V platelet.
    
 0.849
RSAD2
Radical S-adenosyl methionine domain containing 2.
   
  
 0.756
MUC1
SEA domain-containing protein.
     
 0.721
CD4
T-cell surface glycoprotein CD4; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.
    
 0.707
PASK
PAS domain containing serine/threonine kinase.
    
 0.691
CLEC4D
C-type lectin domain family 4 member D.
     
 0.681
GP2
Glycoprotein 2.
   
 0.653
TRIM27
Tripartite motif containing 27.
   
 
 0.629
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.