Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NLRP2NLR family pyrin domain containing 2. (1072 aa)    
Predicted Functional Partners:
PADI6
Peptidyl arginine deiminase 6.
   
 
 0.902
TLE6
WD_REPEATS_REGION domain-containing protein.
    
 
 0.888
OOEP
Oocyte expressed protein isoform 1.
    
 
 0.855
ZNF784
Zinc finger protein 784.
    
 0.714
SCAF11
SR-related CTD associated factor 11.
      
 0.691
NLRC4
NLR family CARD domain containing 4.
   
 
 0.689
PYCARD
PYD and CARD domain containing.
   
 0.675
AK9
Adenylate kinase 9.
   
 
 0.660
GSDMB
Gasdermin B.
  
   
 0.541
PRTG
Protogenin.
    
 
 0.526
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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