STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAC1Uncharacterized protein. (180 aa)    
Predicted Functional Partners:
PAK1
Non-specific serine/threonine protein kinase.
   
 0.991
VAV1
Vav guanine nucleotide exchange factor 1.
   
 0.987
CDC42
Cell division cycle 42.
  
0.986
PAK2
Non-specific serine/threonine protein kinase.
   
 0.985
PAK3
P21 (RAC1) activated kinase 3.
   
 0.982
DOCK2
Dedicator of cytokinesis 2; Belongs to the DOCK family.
   
 0.979
NCKAP1
NCK associated protein 1.
   
 0.979
IQGAP1
IQ motif containing GTPase activating protein 1.
   
 0.977
DOCK1
Dedicator of cytokinesis 1; Belongs to the DOCK family.
   
 0.977
WASL
WASP like actin nucleation promoting factor.
   
 0.975
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.