STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
W5NVE3_SHEEPDUF2439 domain-containing protein. (1055 aa)    
Predicted Functional Partners:
UPF2
UPF2 regulator of nonsense mediated mRNA decay.
   
 0.878
SMG6
SMG6 nonsense mediated mRNA decay factor.
   
 0.875
SMG7
SMG7 nonsense mediated mRNA decay factor.
   
 0.867
CASC3
CASC3 exon junction complex subunit.
    
 0.807
NCBP1
Nuclear cap binding protein subunit 1.
    
 0.803
RBM8A
RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
    
 0.770
SMG5
SMG5 nonsense mediated mRNA decay factor.
   
 0.766
W5PQU7_SHEEP
Uncharacterized protein.
   
 0.766
SMG1
SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family.
    
 
 0.749
DCP1A
Decapping mRNA 1A.
    
 0.748
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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