Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CYBRD1Cytochrome b reductase 1. (204 aa)    
Predicted Functional Partners:
CDYL
Chromodomain Y like.
    
   0.824
MIER1
MIER1 transcriptional regulator.
    
   0.820
MIER2
MIER family member 2.
    
   0.775
SLC40A1
Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
      
 0.725
HAMP
Hepcidin.
      
 0.707
HFE
Homeostatic iron regulator; Belongs to the MHC class I family.
      
 0.635
CDYL2
Chromodomain Y like 2.
    
   0.634
MIER3
MIER family member 3.
    
   0.630
STX4
Syntaxin 4; Belongs to the syntaxin family.
    
   0.614
TFRC
Transferrin receptor.
   
  
 0.589
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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