STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5NVJ1_SHEEPHMG box domain-containing protein. (612 aa)    
Predicted Functional Partners:
CNKSR2
Connector enhancer of kinase suppressor of Ras 2.
      
 0.542
NGLY1
N-glycanase 1.
      
 0.510
DOHH
Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family.
      
 0.504
CEP85
Centrosomal protein 85.
    
 
 0.496
SOX5
SRY-box transcription factor 5.
    
 
0.488
TRIP12
Thyroid hormone receptor interactor 12.
    
 
 0.470
TCF7
Transcription factor 7.
     
0.458
JUP
Junction plakoglobin.
   
 0.447
SHKBP1
SH3KBP1 binding protein 1.
      
 0.436
KLF3
Kruppel like factor 3.
    
 
 0.436
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.