STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARMC3Armadillo repeat containing 3. (871 aa)    
Predicted Functional Partners:
EFCAB1
EF-hand calcium binding domain 1.
   
 
 0.973
C9orf116
Chromosome 9 open reading frame 116.
   
 
 0.971
C4orf47
Chromosome 4 open reading frame 47.
   
  
 0.950
IQUB
IQ motif and ubiquitin domain containing.
   
 
 0.948
CCDC189
Coiled-coil domain containing 189.
      
 0.942
TMEM95
Transmembrane protein 95.
      
 0.938
C5orf49
Chromosome 5 open reading frame 49.
   
  
 0.837
GNGT1
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
      
 0.794
FHAD1
Forkhead associated phosphopeptide binding domain 1.
   
  
 0.738
CCDC170
Coiled-coil domain containing 170.
      
 0.721
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.