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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARL10ADP ribosylation factor like GTPase 10. (212 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
    
 0.833
ITSN1
Intersectin 1.
    
 0.742
GAK
Cyclin G associated kinase.
    
 0.652
GBF1
Golgi brefeldin A resistant guanine nucleotide exchange factor 1.
    
 0.547
COPB1
Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
   
 0.539
ARFGAP1
ADP ribosylation factor GTPase activating protein 1.
   
 0.539
HIGD2A
HIG1 domain-containing protein.
      
 0.536
MYO9B
Myosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.534
MYO9A
Myosin IXA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.534
TMED6
GOLD domain-containing protein.
      
 0.527
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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