STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5NVM2_SHEEPFibronectin type-III domain-containing protein. (186 aa)    
Predicted Functional Partners:
CNTF
Ciliary neurotrophic factor.
    
 0.812
LIF
LIF interleukin 6 family cytokine.
    
 0.751
W5P8P5_SHEEP
Uncharacterized protein.
    
 0.741
W5PDW4_SHEEP
Uncharacterized protein.
    
 0.732
CNTFR
Ciliary neurotrophic factor receptor.
    
 0.639
W5P558_SHEEP
Uncharacterized protein.
      
 0.604
JAK1
Tyrosine-protein kinase.
    
 0.569
TYK2
Tyrosine-protein kinase.
    
 0.561
JAK2
Tyrosine-protein kinase.
    
 0.545
BMPR2
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    
 0.509
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.