STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TTC21ATetratricopeptide repeat domain 21A. (1316 aa)    
Predicted Functional Partners:
DNAH1
Dynein axonemal heavy chain 1.
   
 
 0.931
UNC79
Unc-79 homolog, NALCN channel complex subunit.
   
 0.908
WDR19
WD repeat domain 19.
   
 0.885
IFT122
Intraflagellar transport 122.
   
 0.870
WDR35
WD repeat-containing protein 35; As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in ciliogenesis and ciliary protein trafficking.
   
 0.869
IFT43
Intraflagellar transport 43.
    
 0.867
IFT140
Intraflagellar transport 140.
   
 0.846
CEP135
Centrosomal protein 135.
      
 0.825
IFT74
Intraflagellar transport 74.
   
 0.665
CFAP44
Cilia and flagella associated protein 44.
    
 0.660
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.