| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGO2 | FMR1 | ENSOARP00000004023 | ENSOARP00000010377 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Fragile X mental retardation 1. | 0.830 |
| AGO2 | FXR1 | ENSOARP00000004023 | ENSOARP00000022219 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | FMR1 autosomal homolog 1. | 0.826 |
| AGO2 | SND1 | ENSOARP00000004023 | ENSOARP00000002279 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | 0.782 |
| AGO2 | TSNAX | ENSOARP00000004023 | ENSOARP00000003490 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Uncharacterized protein. | 0.922 |
| EIF3F | PLK1 | ENSOARP00000016377 | ENSOARP00000018616 | Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] | Serine/threonine-protein kinase PLK. | 0.721 |
| EIF3F | RBL2 | ENSOARP00000016377 | ENSOARP00000019087 | Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] | RB transcriptional corepressor like 2. | 0.749 |
| EIF3F | SND1 | ENSOARP00000016377 | ENSOARP00000002279 | Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | 0.715 |
| FMR1 | AGO2 | ENSOARP00000010377 | ENSOARP00000004023 | Fragile X mental retardation 1. | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.830 |
| FMR1 | FXR1 | ENSOARP00000010377 | ENSOARP00000022219 | Fragile X mental retardation 1. | FMR1 autosomal homolog 1. | 0.974 |
| FMR1 | SND1 | ENSOARP00000010377 | ENSOARP00000002279 | Fragile X mental retardation 1. | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | 0.745 |
| FXR1 | AGO2 | ENSOARP00000022219 | ENSOARP00000004023 | FMR1 autosomal homolog 1. | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.826 |
| FXR1 | FMR1 | ENSOARP00000022219 | ENSOARP00000010377 | FMR1 autosomal homolog 1. | Fragile X mental retardation 1. | 0.974 |
| FXR1 | RBM25 | ENSOARP00000022219 | ENSOARP00000000323 | FMR1 autosomal homolog 1. | RNA binding motif protein 25. | 0.511 |
| FXR1 | SND1 | ENSOARP00000022219 | ENSOARP00000002279 | FMR1 autosomal homolog 1. | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | 0.693 |
| MTDH | SND1 | ENSOARP00000004656 | ENSOARP00000002279 | Metadherin. | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | 0.905 |
| PLK1 | EIF3F | ENSOARP00000018616 | ENSOARP00000016377 | Serine/threonine-protein kinase PLK. | Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] | 0.721 |
| PLK1 | RBL2 | ENSOARP00000018616 | ENSOARP00000019087 | Serine/threonine-protein kinase PLK. | RB transcriptional corepressor like 2. | 0.718 |
| PLK1 | SND1 | ENSOARP00000018616 | ENSOARP00000002279 | Serine/threonine-protein kinase PLK. | Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. | 0.723 |
| RBL2 | EIF3F | ENSOARP00000019087 | ENSOARP00000016377 | RB transcriptional corepressor like 2. | Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] | 0.749 |
| RBL2 | PLK1 | ENSOARP00000019087 | ENSOARP00000018616 | RB transcriptional corepressor like 2. | Serine/threonine-protein kinase PLK. | 0.718 |
STRING v12.5 is now available!
