STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DNAJC3DnaJ heat shock protein family (Hsp40) member C3. (505 aa)    
Predicted Functional Partners:
DNAJB11
J domain-containing protein.
   
0.965
EIF2AK2
Eukaryotic translation initiation factor 2 alpha kinase 2.
   
 0.961
DNAJC10
DnaJ homolog subfamily C member 10; Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.
   
0.953
DNAJB1
J domain-containing protein.
   
0.924
HSP90B1
Heat shock protein 90 beta family member 1.
  
 0.907
PDIA6
Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family.
   
 
 0.884
HSPA5
Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.
  
 0.847
HYOU1
Hypoxia up-regulated 1.
  
 0.809
EDEM3
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
    
 
 0.751
XBP1
BZIP domain-containing protein.
   
 
 0.749
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.