STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SYT13Synaptotagmin 13. (366 aa)    
Predicted Functional Partners:
RIMS2
Regulating synaptic membrane exocytosis 2.
     
 0.637
PDZD11
PDZ domain containing 11.
      
 0.614
ITSN2
Intersectin 2.
     
 0.612
KCNK16
Potassium two pore domain channel subfamily K member 16; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
      
 0.609
CSRNP3
Cysteine and serine rich nuclear protein 3.
      
 0.602
HEPHL1
Hephaestin like 1; Belongs to the multicopper oxidase family.
      
 0.597
STXBP5
Syntaxin binding protein 5.
      
 0.579
RAB3C
RAB3C, member RAS oncogene family.
   
 0.572
CACNA1E
Voltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents.
   
 0.554
NXNL2
Nucleoredoxin like 2.
      
 0.551
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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