STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPRUProtein tyrosine phosphatase receptor type U. (1445 aa)    
Predicted Functional Partners:
KIT
Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 0.921
NIPAL1
NIPA like domain containing 1.
      
 0.833
ASB3
Ankyrin repeat and SOCS box containing 3.
    
 
 0.790
TP53RK
TP53 regulating kinase.
   
  
 0.746
MXRA8
Matrix remodeling associated 8.
      
 0.688
DGKZ
Diacylglycerol kinase.
   
  
 0.664
ACP2
Acid phosphatase 2, lysosomal; Belongs to the histidine acid phosphatase family.
   
  
 0.657
GDF2
Growth differentiation factor 2.
   
  
 0.596
MFAP4
Microfibril associated protein 4.
    
 0.587
DLG5
Discs large MAGUK scaffold protein 5; Belongs to the MAGUK family.
   
 
 0.579
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.