| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| IL33 | IL37 | ENSOARP00000014614 | ENSOARP00000022419 | Interleukin 33. | Interleukin-1. | 0.621 |
| IL33 | MYD88 | ENSOARP00000014614 | ENSOARP00000001070 | Interleukin 33. | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] | 0.859 |
| IL33 | TLR4 | ENSOARP00000014614 | ENSOARP00000006210 | Interleukin 33. | TIR domain-containing protein; Belongs to the Toll-like receptor family. | 0.606 |
| IL33 | TRAF6 | ENSOARP00000014614 | ENSOARP00000020492 | Interleukin 33. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.747 |
| IL33 | W5NW40_SHEEP | ENSOARP00000014614 | ENSOARP00000002387 | Interleukin 33. | Ig-like domain-containing protein. | 0.605 |
| IL37 | IL33 | ENSOARP00000022419 | ENSOARP00000014614 | Interleukin-1. | Interleukin 33. | 0.621 |
| IL37 | MYD88 | ENSOARP00000022419 | ENSOARP00000001070 | Interleukin-1. | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] | 0.684 |
| IL37 | TLR4 | ENSOARP00000022419 | ENSOARP00000006210 | Interleukin-1. | TIR domain-containing protein; Belongs to the Toll-like receptor family. | 0.629 |
| IL37 | TRAF6 | ENSOARP00000022419 | ENSOARP00000020492 | Interleukin-1. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.580 |
| IL37 | W5NW40_SHEEP | ENSOARP00000022419 | ENSOARP00000002387 | Interleukin-1. | Ig-like domain-containing protein. | 0.535 |
| LRRC25 | RUVBL1 | ENSOARP00000013186 | ENSOARP00000005333 | Leucine rich repeat containing 25. | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. | 0.554 |
| LRRC25 | SSBP4 | ENSOARP00000013186 | ENSOARP00000012933 | Leucine rich repeat containing 25. | Single stranded DNA binding protein 4. | 0.526 |
| LRRC25 | W5NW40_SHEEP | ENSOARP00000013186 | ENSOARP00000002387 | Leucine rich repeat containing 25. | Ig-like domain-containing protein. | 0.534 |
| MYD88 | IL33 | ENSOARP00000001070 | ENSOARP00000014614 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] | Interleukin 33. | 0.859 |
| MYD88 | IL37 | ENSOARP00000001070 | ENSOARP00000022419 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] | Interleukin-1. | 0.684 |
| MYD88 | RUVBL1 | ENSOARP00000001070 | ENSOARP00000005333 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. | 0.524 |
| MYD88 | TLR4 | ENSOARP00000001070 | ENSOARP00000006210 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] | TIR domain-containing protein; Belongs to the Toll-like receptor family. | 0.999 |
| MYD88 | TRAF6 | ENSOARP00000001070 | ENSOARP00000020492 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.999 |
| MYD88 | W5NSC5_SHEEP | ENSOARP00000001070 | ENSOARP00000001065 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] | CUE domain-containing protein. | 0.869 |
| MYD88 | W5NW40_SHEEP | ENSOARP00000001070 | ENSOARP00000002387 | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes (By similarity). MyD88-mediated signaling in intestinal epithelial cells is cruc [...] | Ig-like domain-containing protein. | 0.725 |