STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5NW69_SHEEPUncharacterized protein. (766 aa)    
Predicted Functional Partners:
DUOXA1
Dual oxidase maturation factor 1.
   
 
 0.836
DUOXA2
Dual oxidase maturation factor 2.
  
 
 0.796
CYBA
Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
   
 0.714
NCF2
Neutrophil cytosolic factor 2.
   
 0.684
NCF1
Neutrophil cytosolic factor 1.
   
 0.667
NOXO1
NADPH oxidase organizer 1.
   
 0.641
NOX3
NADPH oxidase 3.
 
   
 0.518
NOX1
NADPH oxidase 1.
 
   
 0.516
NCF4
Neutrophil cytosolic factor 4.
   
 0.500
NOX4
NADPH oxidase 4.
 
   
 0.483
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.