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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRRC41Leucine rich repeat containing 41. (748 aa)    
Predicted Functional Partners:
RHOBTB3
Rho related BTB domain containing 3.
    
 0.689
CUL5
Cullin 5; Belongs to the cullin family.
    
 0.635
RNF7
Ring finger protein 7.
    
 0.612
ARMT1
Acidic residue methyltransferase 1.
      
 0.537
RBX1
Ring-box 1.
    
 0.525
RHOBTB2
Rho related BTB domain containing 2.
    
 0.502
ASB2
Ankyrin repeat and SOCS box containing 2.
     
 0.497
ZNF318
Zinc finger protein 318.
      
 0.482
CUL2
Cullin 2; Belongs to the cullin family.
     
 0.441
RHOBTB1
Rho related BTB domain containing 1.
    
 0.429
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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