STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PKD2Polycystin 2, transient receptor potential cation channel. (800 aa)    
Predicted Functional Partners:
PKD1
Uncharacterized protein.
 
  
 0.993
W5NPU6_SHEEP
Uncharacterized protein.
 
  
 0.915
W5Q7Y6_SHEEP
Uncharacterized protein.
    
 0.915
TRPC1
Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family.
    
 
 0.866
ARL13B
ADP ribosylation factor like GTPase 13B.
      
 0.836
PACS1
Phosphofurin acidic cluster sorting protein 1.
      
 0.778
PKHD1
PKHD1 ciliary IPT domain containing fibrocystin/polyductin.
      
 0.777
TRPV4
Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family.
      
 0.750
SEC63
SEC63 homolog, protein translocation regulator.
    
 
 0.740
PRKCSH
Protein kinase C substrate 80K-H.
      
 0.733
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.